Eight Days A Week – The Touring Years charts the Fab Four’s rise from gigging in The Cavern Club in their home city of Liverpool, to playing sellout concerts in the United States.
The band’s two surviving members will be joined by Oscar-winning director Ron Howard at the premiere in London’s Leicester Square.
The film, which has the backing of John Lennon’s widow Yoko Ono, and Olivia Harrison, widow of George, features footage showing how the four-piece worked together to become the most successful band the world has seen.
Viewers will also be treated to remastered footage from their historic Shea Stadium concert in New York, the first rock gig played to more than 55,000 people.
The band played their last big concert at Candlestick Park in San Francisco in 1966, and had their last live performance together three years later on the rooftop of their Apple Records headquarters in London.
Liverpool will have the world premiere of the documentary earlier on Thursday evening, following a day of celebrations as the city remembers what is undoubtedly its greatest export.
:: The Beatles: Eight Days A Week – The Touring Years will be released in the UK on Thursday.